Caffeic acid phenethyl ester (CAPE) is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl alcohol. Natural occurrences. CAPE is found in a variety of plants. It is also a component of propolis from honeybee hives. Potential pharmacology
Caffeic Acid Phenethyl Ester is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and immunomodulating activities. Upon administration, caffeic acid phenethyl ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K ...
Natarajan et al (1996) Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc.Natl.Acad.Sci.USA 93 9090 If you know of a relevant reference for Caffeic acid phenethyl ester, please let us know.
Administration of Caffeic acid phenethyl ester (CAPE) by gavage (10 mg/kg body weight per day) for eight weeks results in 50% reduction of tumor volume, suggesting that Caffeic acid phenethyl ester treatment retards the growth of LNCaP 104-R1 xenografts.
Caffeic acid phenethyl ester (CAPE) (Figure 1) is one of the most bioactive components extracted from honeybee hive propolis [26,27]. CAPE treatment exhibits anti-carcinogenic, anti-inflammatory, anti-viral, and immuno-modulatory properties . Several recent studies indicate that CAPE treatment suppresses proliferation, survival, and invasion of ...
Caffeic acid phenethyl ester, an inhibitor of nuclear factor-κB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats. Fitzpatrick et al. J.Pharmacol.Exp.Ther., 2001;299:915 ; Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB.
CAFFEIC ACID PHENETHYL ESTER, 500 mg Be the first to review this item . Available with a Free Business Account. Learn More Specifications for this item. Part Number ...
Caffeic acid phenethyl ester attenuates neuropathic pain by suppressing the p38/NF-kappaB signal pathway in microglia Hao Cheng, Yong Zhang, Weiping Lu, Xianzhong Gao, Chenjie Xu, Hongguang Bao Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China Background: Management of neuropathic pain is still a clinical challenge.
Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the ...
Learn more about Caffeic Acid uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Caffeic Acid
Caffeic acid phenethyl ester (CAPE) is the active component of propolis, a honeybee hive product. 1 Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor, NF-κB. 3, 4 Caffeic acid phenethyl ester inhibits HIV-1 integrase, 5, 6 and also inhibits proliferation of transformed cells.
Protective effects of caffeic acid phenethyl ester on ifosfamide-induced central neurotoxicity in rats, Zeynep Ginis., Toxicol Ind Health October 4, 2013
Phenethyl Caffeate/caffeic Acid Phenethyl Ester Cas 104594-70-9, Find Complete Details about Phenethyl Caffeate/caffeic Acid Phenethyl Ester Cas 104594-70-9,Phenethyl Caffeate,Caffeic Acid Phenethyl Ester,104594-70-9 from Auxiliaries and Other Medicinal Chemicals Supplier or Manufacturer-Shaanxi Yuantai Biological Technology Co., Ltd.
Bio30 New Zealand Propolis has many health benefits due to high levels of important bioflavonoids and caffeic acid phenethyl ester (CAPE). View research here.
Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability.
Caffeic acid is an organic compound that is classified as a hydroxycinnamic acid.This yellow solid consists of both phenolic and acrylic functional groups. It is found in all plants because it is a key intermediate in the biosynthesis of lignin, one of the principal components of woody plant biomass and its residues.
Caffeic acid phenethyl ester (CAPE) is a major propolis component that possesses a variety of pharmacological properties such as antioxidant and anticancer effects. Herein, we investigated the effectiveness of CAPE on cytotoxicity of clinically used anticancer drugs, doxorubicin (DXR) and cisplatin (CDDP), in parental and the drug-resistant cells of stomach (MKN45) and colon (LoVo) cancers.
1. Caffeic Acid Phenethyl Ester–CAS:104594-70-9 . Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties.
AASraw is a manufacturer for bulk production Caffeic Acid Phenethyl Ester under CGMP regulation,and provides online sales,chemical synthetic and customized AASraw provides purity no less than 98% Caffeic Acid Phenethyl Ester (CAPE) raw powder for the an investigational drug for cancer.We are Caffeic Acid Phenethyl Ester powder supplie,CAPE powder for sale,..
Studies are finding that BIO30™ Propolis, a substance made from bee pollen from New Zealand, is rich in vitamins, bioflavonoids, phenolic acids and esters including CAPE (Caffeic Acid Phenethyl Ester) and is an effective treatment in blocking Kinase PAK1.
For instance, rosmarinic acid, a caffeic acid dimer (an ester of caffeic acid and 3,4-dihydroxy-phenyl lactic acid), is common and abundant in Salvia species, and salvianolic acid B, a caffeic acid tetramer, is the major phenolic compound responsible for the high biological activities of Sm and the related species.
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Description: Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays neuroprotective, antioxidant, immunomodulatory and antiinflammatory activities; it also has potential beneficial effects on the wound healing of nasal mucosa in the rat.Caffeic acid phenethyl ester has potential preventive effects on myringosclerosis development after ...
Reviews for Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation World Leading Inhibitor Supplier. United States. Toll Free 866-930 ...
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities. Upon administration, caffeic acid acts as an antioxidant and prevents oxidative stress, thereby preventing DNA damage induced by free radicals.
Caffeic acid phenethyl ester (CAPE) is the active component of propolis, a honeybee hive product. Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor, NF-κB. CAPE has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation.
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